Publications

Journal Article

Carcinogenicity of acrolein, crotonaldehyde, and arecoline
LANCET ONCOLOGY, 22, 19-20 2021
M. Matilde Marques , F. A. Beland , D. W. Lachenmeier , D. H. Phillips , F. L. Chung , D. C. Dorman , S. E. Elmore , S. K. Hammond , S. Krstev , I. Linhart , A. S. Long , D. Mandrioli , K. Ogawa , J. J. Pappas , J. M. Parra Morte , G. Talaska , M. S. Tang , N. Thakur , M. van Tongeren , P. Vineis , IARC Monographs Vol 128 Grp

The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies
PHARMACOLOGICAL RESEARCH, 165, 3 2021
Aline T. Marinho , Joana R. Batuca , Joana P. Miranda , Umbelina Caixas , Clara G. Dias , Teresa Branco , Karina Soto , Pedro F. Pinheiro , Mafalda Bourbon , M. Matilde Marques , Alexandra Maria Moita Antunes , Emilia C. Monteiro , Sofia A. Pereira

Covalent Histone Modification by an Electrophilic Derivative of the Anti-HIV Drug Nevirapine
MOLECULES, 26, 3 2021
Shrika G. Harjivan , Catarina Charneira , Ines L. Martins , Sofia A. Pereira , Guadalupe Espadas , Eduard Sabido , Frederick A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

Acetaminophen Induces an Antioxidative Response in Lettuce Plants
PLANTS-BASEL, 10, 2021
Ines Leitao , Luisa L. Martins , Luisa Carvalho , M. Conceição Oliveira , M. Matilde Marques , Miguel Pedro Mourato

Antimicrobial and antitumor activity of S-methyl dithiocarbazate Schiff base zinc(II) complexes
JOURNAL OF INORGANIC BIOCHEMISTRY, 216, 2021
Filipa Ramilo-Gomes , Yemataw Addis , Israel Tekamo , Isabel Cavaco , Debora L. Campos , Fernando R. Pavan , Clara S. B. Gomes , Vanessa Brito , Adriana O. Santos , Fernanda C. Domingues , Angelo Luis , M. Matilde Marques , J.C. Pessoa , Susana Ferreira , Samuel Silvestre , Isabel Correia

Nevirapine Biotransformation Insights: An Integrated In Vitro Approach Unveils the Biocompetence and Glutathiolomic Profile of a Human Hepatocyte-Like Cell 3D Model
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21, 6 2020
Madalena Cipriano , Pedro F. Pinheiro , Catarina O. Sequeira , Joana S. Rodrigues , Nuno G. Oliveira , Alexandra Maria Moita Antunes , Matilde Castro , M. Matilde Marques , Sofia A. Pereira , Joana P. Miranda

NKp30-A prospective target for new cancer immunotherapy strategies
BRITISH JOURNAL OF PHARMACOLOGY, 177, 4563-4580 10 2020
Pedro F. Pinheiro , Gonçalo C. Justino , M. Matilde Marques

Targeting gliomas with triazene-based hybrids: Structure-activity relationship, mechanistic study and stability
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 172, 16-25 6 2019
Claudia Braga , Ana R. Vaz , M. Conceição Oliveira , M. Matilde Marques , Rui Moreira , Dora Brites , Maria J. Perry

Synthesis, Crystal Structure, and Biological Evaluation of Fused Thiazolo[3,2-a]Pyrimidines as New Acetylcholinesterase Inhibitors
MOLECULES, 24, 6 2019
Mohamed Y. Mahgoub , Awatef M. Elmaghraby , Abd-Elfttah A. Harb , João Ferreira da Silva , Gonçalo C. Justino , M. Matilde Marques

Advisory Group recommendations on priorities for the IARC Monographs
LANCET ONCOLOGY, 20, 763-764 6 2019
M. Matilde Marques , A. Berrington de Gonzalez , F. A. Beland , P. Browne , P. A. Demers , D. W. Lachenmeier , T. Bahadori , D. K. Barupal , F. Belpoggi , P. Comba , R. D. Daniels , C. Ferreccio , O. A. Grigoriev , Y. C. Hong , R. N. Hoover , J. Kanno , M. Kogevinas , G. Lasfargues , R. Malekzadeh , S. Masten , R. Newton , T. Norat , J. J. Pappas , C. Queiroz Moreira , T. Rodriguez , J. Rodriguez-Guzman , V. Sewram , L. Zeise , IARC Monographs Priorities Grp

Advisory Group recommendations on priorities for the IARC Monographs
LANCET ONCOLOGY, 20, 763-764 6 2019
M. Matilde Marques , A. Berrington de Gonzalez , F. A. Beland , P. Browne , P. A. Demers , D. W. Lachenmeier , T. Bahadori , D. K. Barupal , F. Belpoggi , P. Comba , R. D. Daniels , C. Ferreccio , O. A. Grigoriev , Y. C. Hong , R. N. Hoover , J. Kanno , M. Kogevinas , G. Lasfargues , R. Malekzadeh , S. Masten , R. Newton , T. Norat , J. J. Pappas , C. Queiroz Moreira , T. Rodriguez , J. Rodriguez-Guzman , V. Sewram , L. Zeise , IARC Monographs Priorities Grp

Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity
DRUG METABOLISM REVIEWS, 51, 76-90 1 2019
Aline T. Marinho , Joana P. Miranda , Umbelina Caixas , Catarina Charneira , Clara Goncalves-Dias , M. Matilde Marques , Emilia C. Monteiro , Alexandra Maria Moita Antunes , Sofia A. Pereira

Unlocking the Potential of HK2 in Cancer Metabolism and Therapeutics
CURRENT MEDICINAL CHEMISTRY, 26, 7285-7322 2019
Sara N. Garcia , Rita C. Guedes , M. Matilde Marques

High resolution mass spectrometry-based methodologies for identification of Etravirine bioactivation to reactive metabolites: In vitro and in vivo approaches
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 119, 70-82 7 2018
Ana L. A. Godinho , Ines L. Martins , João Pedro da Costa Nunes , Catarina Charneira , Jorge Grilo , Diogo M. Silva , Sofia A. Pereira , Karina Soto , M. Conceição Oliveira , M. Matilde Marques , Cristina C. Jacob , Alexandra M. M. Antunes

How far can we use human serum transferrin to transport drugs?
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256, 8 2018
Jose Justino , M. Matilde Marques

The first-line antiepileptic drug carbamazepine: Reaction with biologically relevant free radicals
FREE RADICAL BIOLOGY AND MEDICINE, 129, 559-568 12 2018
Ines L. Martins , João Pedro da Costa Nunes , Catarina Charneira , Judit Morello , Sofia A. Pereira , J. P. Telo , M. Matilde Marques , Alexandra Maria Moita Antunes

Adverse reactions induced by the antiepileptic drug oxcarbazepine may stem from its metabolic biotransformation to carbamazepine
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256, 8 2018
Ines L. Martins , Catarina Charneira , M. Matilde Marques , Alexandra Antunes

Inducing the activity of NK cells with NKp30 small organic ligands
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256, 8 2018
Pedro F. Pinheiro , Goncalo Justino , Joana Miranda , M. Matilde Marques

Predicting drug metabolites using bacterial-based models
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 256, 8 2018
Pedro Rosado , Josimar Cruz , Marta Justino , M. Matilde Marques , Jose Justino

Carcinogenicity of isobutyl nitrite, beta-picoline, and some acrylates
LANCET ONCOLOGY, 19, 1020-1022 8 2018
Hans Kromhout , Melissa Friesen , M. Matilde Marques , Consolato Maria Sergi , Mohamed Abdallah , Geza Benke , Mark Cesta , Dori Germolec , Keith Houck , Gaku Ichihara , Charles William Jameson , Jun Kanno , Igor Pogribny , Camilla Svendsen , Lamia Benbrahim-Tallaa , Kathryn Z. Guyton , Yann Grosse , Fatiha El Ghissassi , Veronique Bouvard , Amy Hall , Corentin Jaillet , Heidi Mattock , Kurt Straif , Int Agcy Res Canc Monograph Wor

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