Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites
JOURNAL OF INORGANIC BIOCHEMISTRY, 153, 306-314 12 2015
Mariana Fernandez , Esteban Rodriguez Arce , Cynthia Sarniguet , Tânia S. Morais , Ana Isabel Tomaz , Claudio Olea Azar , Roberto Figueroa , J. Diego Maya , Andrea Medeiros , Marcelo Comini , M. Helena Garcia , Lucia Otero , Dinorah Gambino

New water-soluble ruthenium(II) cytotoxic complex: Biological activity and cellular distribution
JOURNAL OF INORGANIC BIOCHEMISTRY, 130, 1-14 1 2014
Tânia S. Morais , Filipa C. Santos , Tiago F. Jorge , Leonor Côrte-Real , Paulo J. Amorim Madeira , Fernanda M. Marques , M Paula Robalo , Antonio Matos , Isabel Santos , M. Helena Garcia

Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 19, 853-867 8 2014
Leonor Côrte-Real , Filipa Mendes , Joana Coimbra , Tânia S. Morais , Ana Isabel Tomaz , Andreia Valente , M. Helena Garcia , Isabel Santos , Manuel Bicho , Fernanda M. Marques

Synthesis, structural characterization and leishmanicidal activity evaluation of ferrocenyl N-heterocyclic compounds
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 745, 299-311 11 2013
Susana Quintal , Tânia S. Morais , Cristina P. Matos , M Paula Robalo , M.Fatima M.Piedade , Maria J. Villa de Brito , M. Helena Garcia , Monica Marques , Carla Maia , Lenea Campino , Joao Madureira

Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands
JOURNAL OF INORGANIC BIOCHEMISTRY, 129, 1-8 12 2013
Ana Cristina Goncalves , Tânia S. Morais , M Paula Robalo , Fernanda M. Marques , Fernando Avecilla , Cristina P. Matos , Isabel Santos , Ana Isabel Tomaz , M. Helena Garcia

Biological activity and cellular uptake of [Ru(eta(5)-C5H5)(PPh3)(Me(2)bpy)][CF3SO3] complex
JOURNAL OF INORGANIC BIOCHEMISTRY, 122, 8-17 5 2013
Tânia S. Morais , Filipa C. Santos , Leonor Côrte-Real , Fernanda M. Marques , M Paula Robalo , Paulo J. Amorim Madeira , M. Helena Garcia

Exploring the effect of the ligand design on the interactions between [Ru(eta(5)-C5H5)(PPh3)(N,O)][CF3SO3] complexes and human serum albumin
JOURNAL OF INORGANIC BIOCHEMISTRY, 129, 94-101 12 2013
Tânia S. Morais , Filipa C. Santos , Leonor Côrte-Real , M. Helena Garcia

Cellular Uptake Mechanisms of an Antitumor Ruthenium Compound: The Endosomal/Lysosomal System as a Target for Anticancer Metal-Based Drugs
MICROSCOPY AND MICROANALYSIS, 19, 1122-1130 10 2013
Leonor Côrte-Real , A. P. Alves de Matos , Irina Alho , Tânia S. Morais , Ana Isabel Tomaz , M. Helena Garcia , Isabel Santos , Manuel Bicho , Fernanda M. Marques

Synthesis and structural characterization of new piano-stool ruthenium(II) complexes bearing 1-butylimidazole heteroaromatic ligand
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 713, 112-122 8 2012
Tânia S. Morais , M. Helena Garcia , M Paula Robalo , M.Fatima M.Piedade , M. Teresa Duarte , Maria J. Villa de Brito , Paulo J. Amorim Madeira

Synthesis of organometallic ruthenium(II) complexes with strong activity against several human cancer cell lines
JOURNAL OF INORGANIC BIOCHEMISTRY, 114, 65-74 9 2012
Tânia S. Morais , Tiago J. L. Silva , Fernanda M. Marques , M Paula Robalo , Fernando Avecilla , Paulo J. Amorim Madeira , Paulo Mendes , Isabel Santos , M. Helena Garcia

[Ru-II(eta(5)-C5H5)(bipy)(PPh3)](+), a promising large spectrum antitumor agent: Cytotoxic activity and interaction with human serum albumin
JOURNAL OF INORGANIC BIOCHEMISTRY, 117, 261-269 12 2012
Ana Isabel Tomaz , Tamas Jakusch , Tânia S. Morais , Fernanda M. Marques , R. F. M. de Almeida , Filipa Mendes , Eva A. Enyedy , Isabel Santos , J.C. Pessoa , Tamas Kiss , M. Helena Garcia

Gas-phase behaviour of Ru(II) cyclopentadienyl-derived complexes with N-coordinated ligands by electrospray ionization mass spectrometry: fragmentation pathways and energetics
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 26, 1675-1686 8 2012
Paulo J. Amorim Madeira , Tânia S. Morais , Tiago J. L. Silva , Pedro Florindo , M. Helena Garcia

DNA interaction and cytotoxicity studies of new ruthenium(II) cyclopentadienyl derivative complexes containing heteroaromatic ligands
JOURNAL OF INORGANIC BIOCHEMISTRY, 105, 241-249 2 2011
Virtudes Moreno , Merce Font-Bardia , Teresa Calvet , Julia Lorenzo , Francesc X. Aviles , M. Helena Garcia , Tânia S. Morais , Andreia Valente , M Paula Robalo

New ruthenium(II) mixed metallocene derived complexes: Synthesis, characterization by X-ray diffraction and evaluation on DNA interaction by atomic force microscopy
INORGANICA CHIMICA ACTA, 363, 3765-3775 11 2010
M. Helena Garcia , Andreia Valente , Pedro Florindo , Tânia S. Morais , M.Fatima M.Piedade , M. Teresa Duarte , Virtudes Moreno , Francesc X. Aviles , Julia Loreno

Studies of the Antiproliferative Activity of Ruthenium (II) Cyclopentadienyl-Derived Complexes with Nitrogen Coordinated Ligands
BIOINORGANIC CHEMISTRY AND APPLICATIONS, , 2010
Virtudes Moreno , Julia Lorenzo , Francesc X. Aviles , M. Helena Garcia , Joao P. Ribeiro , Tânia S. Morais , Pedro Florindo , M Paula Robalo

Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands
JOURNAL OF INORGANIC BIOCHEMISTRY, 103, 354-361 3 2009
M. Helena Garcia , Tânia S. Morais , Pedro Florindo , M.Fatima M.Piedade , Virtudes Moreno , Carlos Ciudad , Veronica Noe