Characterization of the antiproliferative potential and biological targets of a trans ketoimine platinum complex
INORGANICA CHIMICA ACTA, 423, 156-167 11 2014
Joana Silva , Antonio Sebastiao Rodrigues , Paula A. Videira , Jamal Lasri , Adilia Charmier , Armando J.L. Pombeiro , A.R. Fernandes

Insights into the mechanisms underlying the antiproliferative potential of a Co(II) coordination compound bearing 1,10-phenanthroline-5,6-dione: DNA and protein interaction studies
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 19, 787-803 8 2014
Daniel V. Luis , Joana Silva , Ana Isabel Tomaz , R. F. M. de Almeida , Miguel Larguinho , Pedro V. Baptista , L.M.D.R.S. Martins , Telma F. S. Silva , Pedro M. Borralho , Cecilia M. P. Rodrigues , Antonio Sebastiao Rodrigues , Armando J.L. Pombeiro , A.R. Fernandes

Gold-nanobeacons for gene therapy: evaluation of genotoxicity, cell toxicity and proteome profiling analysis
NANOTOXICOLOGY, 8, 521-532 8 2014
Joao Conde , Miguel Larguinho , Ana Cordeiro , L. R. Raposo , Pedro M. Costa , Susana Santos , Mario Diniz , A.R. Fernandes , Pedro V. Baptista

Di- and tri-organotin(IV) complexes of arylhydrazones of methylene active compounds and their antiproliferative activity
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 760, 67-73 6 2014
Kamran T. Mahmudov , M. Fátima C. Guedes da Silva , Maximilian N. Kopylovich , A.R. Fernandes , Ana Silva , Archana Mizar , Armando J.L. Pombeiro

Cobalt Complexes with Pyrazole Ligands as Catalyst Precursors for the Peroxidative Oxidation of Cyclohexane: X-ray Absorption Spectroscopy Studies and Biological Applications
CHEMISTRY-AN ASIAN JOURNAL, 9, 1132-1143 4 2014
Telma F. S. Silva , L.M.D.R.S. Martins , M. Fátima C. Guedes da Silva , Maxim L. Kuznetsov , A.R. Fernandes , Ana Silva , Chun-Jern Pan , Jyh-Fu Lee , Bing-Joe Hwang , Armando J.L. Pombeiro

Organometallic Compounds in Cancer Therapy: Past Lessons and Future Directions
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 14, 1199-1212 2014
Pedro Martins , Mara Marques , Lidia Coito , Armando J.L. Pombeiro , Pedro V. Baptista , A.R. Fernandes

Exosome in Tumour Microenvironment: Overview of the Crosstalk between Normal and Cancer Cells
BIOMED RESEARCH INTERNATIONAL, , 2014
Catarina Roma-Rodrigues , A.R. Fernandes , Pedro V. Baptista

AuNPs for identification of molecular signatures of resistance
FRONTIERS IN MICROBIOLOGY, 5, 8 2014
Bruno Veigas , A.R. Fernandes , Pedro V. Baptista

Novel insights in hypertrophic cardiomyopathy (HCM) evaluation: mirs as biomarkers of HCM cardiac remodeling
EUROPEAN JOURNAL OF HEART FAILURE, 12, S30 5 2013
S. Santos , V. Marques , A. C. Nunes , A. T. Freitas , M. R. Gouveia , M. Antunes , I. M. Carreira , I. M. Gaspar , C. Monteiro , A.R. Fernandes

Cobalt and Zinc Compounds Bearing 1,10-Phenanthroline-5,6-dione or 1,3,5-Triaza-7-phosphaadamantane Derivatives - Synthesis, Characterization, Cytotoxicity, and Cell Selectivity Studies
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2013, 3651-3658 7 2013
Telma F. S. Silva , P. Smolenski , L.M.D.R.S. Martins , M. Fátima C. Guedes da Silva , A.R. Fernandes , Daniel Luis , Ana Silva , Susana Santos , Pedro M. Borralho , Cecilia M. P. Rodrigues , Armando J.L. Pombeiro

Instability of mRNA expression signatures of drug transporters in chronic myeloid leukemia patients resistant to imatinib
ONCOLOGY REPORTS, 29, 741-750 2 2013
Marta Gromicho , Marta Magalhaes , Fatima Torres , Joana Dinis , A.R. Fernandes , Paula Rendeiro , Purificacao Tavares , Antonio Laires , Jose Rueff , Antonio Sebastiao Rodrigues

High resolution melting: improvements in the genetic diagnosis of hypertrophic cardiomyopathy in a Portuguese cohort
BMC MEDICAL GENETICS, 13, 3 2012
Susana Santos , Vanda Marques , Marina Pires , Leonor Silveira , Helena Oliveira , Vasco Lanca , Dulce Brito , Hugo Madeira , J. Fonseca Esteves , Antonio Freitas , Isabel M. Carreira , Isabel M. Gaspar , Carolino Monteiro , A.R. Fernandes

Cobalt complexes bearing scorpionate ligands: synthesis, characterization, cytotoxicity and DNA cleavage
DALTON TRANSACTIONS, 41, 12888-12897 2012
Telma F. S. Silva , L.M.D.R.S. Martins , M. Fátima C. Guedes da Silva , A.R. Fernandes , Ana Silva , Pedro M. Borralho , Susana Santos , Cecilia M. P. Rodrigues , Armando J.L. Pombeiro

Development of imatinib and dasatinib resistance: dynamics of expression of drug transporters ABCB1, ABCC1, ABCG2, MVP, and SLC22A1
LEUKEMIA \& LYMPHOMA, 52, 1980-1990 10 2011
Marta Gromicho , Joana Dinis , Marta Magalhaes , A.R. Fernandes , Purificacao Tavares , Antonio Laires , Jose Rueff , Antonio Sebastiao Rodrigues

Genetic diagnosis of hypertrophic cardiomyopathy using mass spectrometry DNA arrays and high resolution melting
REVISTA PORTUGUESA DE CARDIOLOGIA, 30, 7-18 1 2011
Susana Santos , Vasco Lanca , Helena Oliveira , Patricia Branco , Leonor Silveira , Vanda Marques , Dulce Brito , Hugo Madeira , Manuel Bicho , A.R. Fernandes

The RIM101 pathway has a role in Saccharomyces cerevisiae adaptive response and resistance to propionic acid and other weak acids
FEMS YEAST RESEARCH, 9, 202-216 3 2009
Nuno P. Mira , Artur B. Lourenco , A.R. Fernandes , Jorg D. Becker , Isabel Sa-Correia

An e6a2 BCR-ABL fusion transcript in a CML patient having an iliac chloroma at initial presentation
LEUKEMIA \& LYMPHOMA, 48, 1034-1037 2007
Fatima Torres , Anna Ivanova-Dragoeva , Monica Pereira , Joana Veiga , Antonio S. Rodrigues , Aida Botelho Sousa , Purificacao Tavares , A.R. Fernandes

Saccharomyces cerevisiae multidrug resistance transporter Qdr2 is implicated in potassium uptake, providing a physiological advantage to quinidine-stressed cells
EUKARYOTIC CELL, 6, 134-142 2 2007
Rita C. Vargas , Raul Garcia-Salcedo , Sandra Tenreiro , Miguel C. Teixeira , A.R. Fernandes , Jose Ramos , Isabel Sa-Correia

Three novel mutations of the myelin Po gene (MPZ) in Portuguese families with CMT1B
NEUROMUSCULAR DISORDERS, 16, 665 10 2006
T. Coelho , M. Santos , R. Cerqueira , M. M. Pires , L. Lameiras , H. Gabriel , A.R. Fernandes , P. Tavares , A. Guimaraes

The SPI1 gene, encoding a glycosylphosphatidylinositol-anchored cell wall protein, plays a prominent role in the development of yeast resistance to lipophilic weak-acid food preservatives
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72, 7168-7175 11 2006
T. Simoes , N. P. Mira , A.R. Fernandes , Isabel Sa-Correia