PON-1 activity as a protective player in nevirapine hepatotoxicity: Data comparison in 2D and 3D cell cultures
TOXICOLOGY LETTERS, 229, S134-S135 9 2014
Aline T. Marinho , Clara G. Dias , Pedro F. Pinheiro , Alexandra Maria Moita Antunes , M. Matilde Marques , Emilia C. Monteiro , Joana P. Miranda , Sofia A. Pereira

Sex differences in hepatic and intestinal contributions for nevirapine biotransformation
TOXICOLOGY LETTERS, 229, S240-S241 9 2014
Pedro F. Pinheiro , Aline T. Marinho , Alexandra Maria Moita Antunes , M. Matilde Marques , Matilde F. Castro , Sofia A. Pereira , Joana P. Miranda

Covalent histone modification by nevirapine: Potential association with non-AIDS defining cancers
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 248, 8 2014
Shrika G. Harjivan , Catarina Sofia Romão Charneira , Sofia A. Pereira , Guadalupe Espadas , Eduard Sabido , Frederick A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

The phenolic metabolites of the anti-HIV drug efavirenz: Evidence for distinct reactivities upon oxidation with Fremy s salt
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 74, 7-11 3 2014
Shrika G. Harjivan , Riccardo Wanke , João Ferreira da Silva , M. Matilde Marques , Alexandra Maria Moita Antunes

Bioactivation to an aldehyde metabolite-Possible role in the onset of toxicity induced by the anti-HIV drug abacavir
TOXICOLOGY LETTERS, 224, 416-423 1 2014
Nadia M. Grilo , Catarina Sofia Romão Charneira , Sofia A. Pereira , Emilia C. Monteiro , M. Matilde Marques , Alexandra Maria Moita Antunes

Development and validation of an HPLC-UV method for quantifying nevirapine and its main phase I metabolites in human blood
ANALYTICAL METHODS, 6, 1575-1580 2014
Aline T. Marinho , Ana L. A. Godinho , David A. Novais , Alexandra Maria Moita Antunes , M. Matilde Marques , Teresa Ramos , Clara G. Dias , Emilia C. Monteiro , Sofia A. Pereira

Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 69, 476-482 2 2014
Aline T. Marinho , Patrcia M. Rodrigues , Umbelina Caixas , Alexandra Maria Moita Antunes , Teresa Branco , Shrika G. Harjivan , M. Matilde Marques , Emlia C. Monteiro , Sofia A. Pereira

Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells (vol 28, pg 721, 2013)
MUTAGENESIS, 29, 97 1 2014
Susana Bandarra , Ana S. Fernandes , Ines Magro , Patricia S. Guerreiro , Marta Pingarilho , Mona I. Churchwell , Octavia Monteiro Gil , Ines Batinic-Haberle , Sandrina Goncalves , Jose Rueff , Joana P. Miranda , M. Matilde Marques , Frederick A. Beland , Matilde Castro , Jorge F. Gaspar , Nuno G. Oliveira

Estrogen-induced systemic lupus erythematosus: Understanding the role of protein adducts in autoimmunity
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 246, 9 2013
Catarina Sofia Romão Charneira , Sofia A. Pereira , Alexandra Maria Moita Antunes , M. Matilde Marques

3D hepatocyte cultures: A useful tool in the study of Nevirapine bioactivation and toxicity
TOXICOLOGY LETTERS, 221, S174 8 2013
Joana P. Miranda , Pedro F. Pinheiro , A. T. Marinho , S. G. Harjivan , Matilde Castro , S. A. Pereira , Alexandra Maria Moita Antunes , M. Matilde Marques

Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells
MUTAGENESIS, 28, 721-729 11 2013
Susana Bandarra , Ana S. Fernandes , Ines Magro , Patricia S. Guerreiro , Marta Pingarilho , Mona I. Churchwell , Octavia Monteiro Gil , Ines Batinic-Haberle , Sandrina Goncalves , Jose Rueff , Joana P. Miranda , M. Matilde Marques , Frederick A. Beland , Matilde Castro , Jorge F. Gaspar , Nuno G. Oliveira

Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity
BIOORGANIC \& MEDICINAL CHEMISTRY LETTERS, 23, 4669-4673 8 2013
Edson dos A. dos Santos , Ernest Hamel , Ruoli Bai , James C. Burnett , Camila Santos Suniga Tozatti , Danielle Bogo , Renata T. Perdomo , Alexandra Maria Moita Antunes , M. Matilde Marques , Maria de F. C. Matos , Denis P. de Lima

Monitoring abacavir bioactivation in humans: Screening for an aldehyde metabolite
TOXICOLOGY LETTERS, 219, 59-64 5 2013
Nadia M. Grilo , Alexandra Maria Moita Antunes , Umbelina Caixas , Aline T. Marinho , Catarina Sofia Romão Charneira , M. Conceição Oliveira , Emlia C. Monteiro , M. Matilde Marques , Sofia A. Pereira

2 -Deoxythymidine Adducts from the Anti-HIV Drug Nevirapine
MOLECULES, 18, 4955-4971 5 2013
Alexandra Maria Moita Antunes , Benjamin Wolf , M. Conceição Oliveira , Frederick A. Beland , M. Matilde Marques

Carcinogenicity of acrylamide in B6C3F(1) mice and F344/N rats from a 2-year drinking water exposure
FOOD AND CHEMICAL TOXICOLOGY, 51, 149-159 1 2013
Frederick A. Beland , Paul W. Mellick , Greg R. Olson , Maria C. B. Mendoza , M. Matilde Marques , Daniel R. Doerge

The role of competitive binding to human serum albumin on efavirenz-warfarin interaction: a nuclear magnetic resonance study
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 42, 443-446 11 2013
Riccardo Wanke , Shrika G. Harjivan , Sofia A. Pereira , M. Matilde Marques , Alexandra Maria Moita Antunes

Synthesis of catecholamine conjugates with nitrogen-centered bionucleophiles
BIOORGANIC CHEMISTRY, 44, 19-24 10 2012
Filipa Siopa , Alice S. Pereira , Luisa M. Ferreira , M. Matilde Marques , Paula S. Branco

Hemoglobin adducts from the antiretroviral abacavir in HIV-infected patients as evidence of bioactivation
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 244, 8 2012
Nadia M. Grilo , Alexandra Maria Moita Antunes , Umbelina Caixas , Sandra Gouveia , M. Conceição Oliveira , Aline T. Marinho , Emilia C. Monteiro , M. Matilde Marques , Sofia A. Pereira

Oxidation of phenolic nevirapine metabolites to a reactive quinone - a plausible pathway to toxicity
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 244, 8 2012
David A. Novais , Shrika G. Harjivan , Riccardo Wanke , Pedro F. Pinheiro , Pedro P. Santos , Frederick A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

Binding of the anti-HIV drug Efavirenz to human serum albumin: A F-19-NMR study
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 244, 8 2012
Riccardo Wanke , Shrika G. Harjivan , M. Matilde Marques , Alexandra Maria Moita Antunes