New hydroxypyridinone-functionalized sepharoses as sorbing agents for hard metal ions
JOURNAL OF HAZARDOUS MATERIALS, 186, 1902-1908 2 2011
Raquel Grazina , M. Amélia Santos

A gallium complex with a new tripodal tris-hydroxypyridinone for potential nuclear diagnostic imaging solution and in vivo studies of Ga-67-labeled species
JOURNAL OF INORGANIC BIOCHEMISTRY, 105, 31-38 1 2011
Sílvia Chaves , Ana C. Mendonca , Sergio M. Marques , M. Isabel Prata , Ana C. Santos , Andre F. Martins , Carlos F. G. C. Geraldes , M. Amélia Santos

New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors (vol 20, pg 3623, 2010)
BIOORGANIC \& MEDICINAL CHEMISTRY LETTERS, 20, 7554 12 2010
M. Alexandra Esteves , Osvaldo Ortet , Anabela Capelo , Claudiu T. Supuran , Sergio M. Marques , M. Amélia Santos

Syntheses and characterization of Cu2+, Ni2+ and Zn2+ binding capability of histidinehydroxamic acid derivatives
POLYHEDRON, 29, 3137-3145 10 2010
Edit Csapo , Peter Buglyo , Nora Veronika Nagy , M. Amélia Santos , Alma Corona , Etelka Farkas

Pteridine-sulfonamide conjugates as dual inhibitors of carbonic anhydrases and dihydrofolate reductase with potential antitumor activity
BIOORGANIC \& MEDICINAL CHEMISTRY, 18, 5081-5089 7 2010
Sergio M. Marques , Eva A. Enyedy , Claudiu T. Supuran , Natalia I. Krupenko , Sergey A. Krupenko , M. Amélia Santos

New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors
BIOORGANIC \& MEDICINAL CHEMISTRY LETTERS, 20, 3623-3627 6 2010
M. Alexandra Esteves , Osvaldo Ortet , Anabela Capelo , Claudiu T. Supuran , Sergio M. Marques , M. Amélia Santos

New Tris(hydroxypyridinones) as Iron and Aluminium Sequestering Agents: Synthesis, Complexation and In Vivo Studies
CHEMISTRY-A EUROPEAN JOURNAL, 16, 10535-10545 2010
Sílvia Chaves , Sergio M. Marques , Andre M. F. Matos , Andreia Nunes , Lurdes Gano , Tiziano Tuccinardi , Adriano Martinelli , M. Amélia Santos

Complexes of hydroxy(thio)pyrone and hydroxy(thio)pyridinone with Zn(II) and Mo(VI). Thermodynamic stability and insulin-mimetic activity
METALLOMICS, 2, 220-227 2010
Sílvia Chaves , Ratomir Jelic , Catarina Mendonca , Marta P. Carrasco , Yutaka Yoshikawa , Hiromu Sakurai , M. Amélia Santos

Combined chelation based on glycosyl-mono- and bis-hydroxypyridinones for aluminium mobilization: Solution and biodistribution studies
JOURNAL OF INORGANIC BIOCHEMISTRY, 103, 1521-1529 11 2009
Sílvia Chaves , Paul I. Dron , Florina A. Danalache , Diana Sacoto , Lurdes Gano , M. Amélia Santos

Multitemplate Alignment Method for the Development of a Reliable 3D-QSAR Model for the Analysis of MMP3 Inhibitors
JOURNAL OF CHEMICAL INFORMATION AND MODELING, 49, 1715-1724 7 2009
Tiziano Tuccinardi , Gabriella Ortore , M. Amélia Santos , Sergio M. Marques , Elisa Nuti , Armando Rossello , Adriano Martinelli

New tripodal hydroxypyridinone based chelating agents for Fe(III), Al(III) and Ga(III): Synthesis, physico-chemical properties and bioevaluation
JOURNAL OF INORGANIC BIOCHEMISTRY, 103, 262-273 2 2009
Raquel Grazina , Lurdes Gano , Jaroslav Sebestik , M. Amélia Santos

Combined chelation of bi-functional bis-hydroxypiridinone and mono-hydroxypiridinone: Synthesis, solution and in vivo evaluation
JOURNAL OF INORGANIC BIOCHEMISTRY, 103, 288-298 2 2009
Sofia Gama , Marco Gil , Lurdes Gano , Etelka Farkas , M. Amélia Santos

A bis(3-hydroxy-4-pyridinone)-EDTA derivative as a strong chelator for M3+ hard metal ions: complexation ability and selectivity
DALTON TRANSACTIONS, , 6141-6150 2009
Sofia Gama , Paul Dron , Sílvia Chaves , Etelka Farkas , M. Amélia Santos

Dual Inhibitors of Matrix Metalloproteinases and Carbonic Anhydrases: Iminodiacetyl-Based Hydroxamate-Benzenesulfonamide Conjugates
JOURNAL OF MEDICINAL CHEMISTRY, 51, 7968-7979 12 2008
Sergio M. Marques , Elisa Nuti , Armando Rossello , Claudiu T. Supuran , Tiziano Tuccinardi , Adriano Martinelli , M. Amélia Santos

Biologically relevant O,S-donor compounds. Synthesis, molybdenum complexation and xanthine oxidase inhibition
DALTON TRANSACTIONS, , 1773-1782 4 2008
Sílvia Chaves , Marco Gil , Sonia Canario , Ratomir Jelic , Maria J. Romao , Jose Trincao , Eberhardt Herdtweck , Joana Sousa , Carmen Diniz , Paula Fresco , M. Amélia Santos

Recent developments on 3-hydroxy-4-pyridinones with respect to their clinical applications - Mono and combined ligand approaches
COORDINATION CHEMISTRY REVIEWS, 252, 1213-1224 5 2008
M. Amélia Santos

New hydroxypyridinone iron-chelators as potential anti-neurodegenerative drugs
FRONTIERS IN BIOSCIENCE-LANDMARK, 13, 6763-6774 5 2008
Daniela Arduino , Daniel Silva , Sandra M. Cardoso , Sílvia Chaves , Catarina R. Oliveira , M. Amélia Santos

A new approach for potential combined chelation therapy using mono- and bis-hydroxypyridinones
HEMOGLOBIN, 32, 147-156 2008
M. Amélia Santos , Sofia Gama , Marco Gil , Lurdes Gano

Complexation of molybdenum(VI) with bis(3-hydroxy-4-pyridinone)amino acid derivatives
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, , 1728-1737 4 2007
M. Amélia Santos , Sofia Gama , J.C. Pessoa , M. Conceição Oliveira , Imre Toth , Etelka Farkas

Carbonic anhydrase inhibitors: Inhibition of cytosolic/tumor-associated isoforms I, II, and IX with iminodiacetic carboxylates/hydroxamates also incorporating benzenesulfonamide moieties
BIOORGANIC \& MEDICINAL CHEMISTRY LETTERS, 17, 1538-1543 3 2007
M. Amélia Santos , Sergio M. Marques , Daniela Vullo , Alessio Innocenti , Andrea Scozzafava , Claudiu T. Supuran