| Abstract |
Hydrogen sulphide has therapeutic functions but because it is a gas its delivery as a drug poses specific difficulties. Porous materials have been emerging as serious candidates for the storage and release of small gas molecules with therapeutic effects. In this work, we study microporous (A, and Y zeolites; ETS-4 and ETS-10 titanosilicates) and mesoporous (SBA-15 with and without surface amines functionalization) materials. The experimental determination of the H2S amounts released from the porous materials in liquid phase was challenging. For this, two methodologies were used, the detection through the methylene blue reaction and by a selective electrode. In the end, considering the storage amounts, the release profile and the cytotoxicity, 4A zeolite and ETS-10 titanosilicate showed the best properties. |
