| Publication Type |
Journal Article |
| Title |
Association between tipranavir plasma levels and virological response in HIV-Infected patients |
| Authors |
Judit Morello Pilar Garcia Gasco Sonia Rodriguez-Novoa Carmen de Mendoza Francisco Blanco Gema Gonzalez-Pardo Beatriz Sanz Inmaculada Jimenez-Nacher Vincent Soriano |
| Groups |
|
| Journal |
AIDS RESEARCH AND HUMAN RETROVIRUSES |
| Year |
2008 |
| Month |
March |
| Volume |
24 |
| Number |
3 |
| Pages |
389-391 |
| Abstract |
The impact of tipranavir plasma levels (TPV C-min) on virological response was examined in 36 antiretroviral-experienced HIV-infected individuals. Although TPV Cmin did not predict outcome in patients with less than five or more than eight baseline TPV-associated resistance mutations, TPV C-min values were greater in responders than in nonresponders with five to seven baseline TPV-associated resistance mutations (38.8 vs. 13.8 g/ml, p = 0.017). Thus, therapeutic drug monitoring might be helpful in ensuring a viral response in this subset of patients. |
| DOI |
http://dx.doi.org/10.1089/aid.2007.0225 |
| ISBN |
|
| Publisher |
|
| Book Title |
|
| ISSN |
0889-2229 |
| EISSN |
|
| Conference Name |
|
| Bibtex ID |
ISI:000254735200007 |
| Observations |
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