Publication Type Journal Article
Title Molecular Salts of L-Carnosine: Combining a Natural Antioxidant and Geroprotector with Generally Regarded as Safe (GRAS) Organic Acids
Authors Oleksii Shemchuk Vânia André M. Teresa Duarte Paola Taddei Katia Rubini Dario Braga Fabrizia Grepioni
Groups BioMol
Journal CRYSTAL GROWTH \& DESIGN
Year 2017
Month June
Volume 17
Number 6
Pages 3379-3386
Abstract The potent natural hydrophilic antioxidant L-carnosine has been reacted with a number of organic acids belonging to the generally regarded as safe (GRAS) group, resulting in the preparation of 11 new crystalline salts, which were characterized by X-ray powder diffraction and thermal analysis; the structures of six of them were determined from powder data, and one was fully characterized via single crystal data. The reaction with folic acid resulted in an amorphous folate salt, which was characterized by a combination of thermal methods and Raman spectroscopy; the solubility of the folate salt was also measured and found to be comparable to that of the commercial sodium folate.
DOI http://dx.doi.org/10.1021/acs.cgd.7b00345
ISBN
Publisher AMER CHEMICAL SOC
Book Title
ISSN 1528-7483
EISSN 1528-7505
Conference Name
Bibtex ID ISI:000403136200055
Observations
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