Dissemination

The topic of my research is the sustainable synthesis of novel potentially bioactive nucleoside analogs.

It is a unique work since we can synthesize complex nucleosides using innovative and green methods. The synthesized molecules can potentially interact with biological targets responsible for many life treating diseases.

The biggest challenges consist in using green methods for the synthesis of carbohydrates, since carbohydrates and green chemistry are not very compatible. However, step by step we will continue to try and overcome every drawback along the way.

Science is a very big part of my every day; however, I always give space to family and friends. Beyond that I think traveling, reading, and music are a must for mental health, and as a form of coping with the drawbacks of investigation life.

My research focuses on developing innovative, biocompatible, multi-layered hydrogel dressings tailored for malignant fungating wounds (MFW), which affect advanced cancer patients and are often non-healable. These dressings combine synthetic and natural polymers (like poly vinyl alcohol, chitosan, casein, and starch) with natural-origin therapeutic agents (e.g., Calendula extract, essential oils), aiming to manage pain, exudate, bleeding, odour, and infection —improving patient comfort and care.

MFW are mainly managed using dressings intended for other types of chronic wounds, which are incapable of efficiently address the needs of MFW. This project is unique in its holistic, multifunctional approach—blending sustainable materials with drug delivery systems and advanced formulation strategies (e.g., cyclodextrins, biodegradable coatings) to address both physical and psychological burdens of MFW. It is also exploring novel antimicrobial agents and affordable alternatives like Serratia rubidaea-derived prodigiosin.

The main challenges lie in ensuring efficient drug release, maintaining material performance post-sterilisation, and balancing efficacy, cost, and biocompatibility for future clinical translation.

Beyond science, family is a cornerstone of my well-being, bringing me joy and support regarding the challenges of research. In my spare time, I find great fulfilment in staying active, especially through trekking in nature and love visiting historical sites.

I am working towards developing sustainable methodologies for organic synthesis, focusing on enantioselective C(sp³)–N and C(sp³)–O bonds, by expanding the reactivity of transition metal (TM) complexes based on earth-abundant metal centres (Fe, Ni). My project also entails the development of new TM complexes to access industrially relevant compounds.

Given the relevance of heteroatom-containing chiral molecules, there is a need to develop enantioselective C–N and C–O bond formation reactions, which are far less explored than their C–C counterparts. Moreover, there is higher focus on C(sp²)-heteroatom bonds than C(sp³)-heteroatom bonds.

Developing sustainable processes remains a challenge in the construction of C-heteroatom bonds by transition metal-catalyzed asymmetric C–H functionalization, as the state-of-art is limited to precious metal catalysts (Pd, Rh, Ru, etc). Furthermore, enantioselective C(sp³)–O bond forming reactions are a major challenge within asymmetric C–H functionalization.

I love to travel, bake and run.

My research focuses on developing advanced asymmetric mixed matrix membranes using poly(ionic liquid)s and ionic liquids with particle fillers to enhance gas permeability. These materials are designed for efficient CO₂ separation, contributing to industrial applications. 

Poly(ionic liquid)s are uniquely advantageous due to their exceptional stability, tunability, and absence of vapor pressure, allowing them to endure high temperatures without losing functionality. By integrating these polymers with carefully selected fillers, the membranes achieve enhanced gas permeability, maximizing separation performance and expanding their application potential. This combination makes them more effective and versatile compared to traditional gas separation.

The biggest challenges involve optimizing the polymer-filler interaction for uniformity and stability, the fabrication of tinner membranes, and overcoming the trade-off between permeability and selectivity. Achieving high CO₂ flux without losing selectivity requires meticulous material optimization and design.

Beyond science, I dedicate my time to being an active member of a non-profit organization that promotes and organizes events in my hometown. Additionally, I value spending quality time with my family, especially enjoying moments with my one-year-old daughter.

I support CQE researchers in identifying and preparing applications for competitive national and international (non-Horizon Europe) funding opportunities that best align with their goals, fostering the impact of their project ideas, and promoting the valorization of their research assets.

It combines an interdisciplinary approach, essential for understanding the scientific and technical aspects of the research conducted by CQE researchers, with strategic thinking to support them in navigating grant application processes and facilitating collaborations with partners across different sectors to maximize research impact.

The lack of well-defined calendars from various funding entities and the challenge of encouraging researchers to also consider research impact and knowledge valorization.

When I am not working, I really enjoy spending time with my family and reading.

I have a profound passion for inorganic chemistry and electrochemistry, which I have pursued throughout my career. During my PhD, I deepened my expertise in the redox properties and reactivity of metal complexes and materials. Currently, my research focuses on the electrosynthesis of metal-organic framework (MOF) films. I explore their applications in energy-related processes, such as CO₂ conversion, and their potential integration into electronic devices. 

My work is unique as it integrates inorganic chemistry, electrochemistry, and materials science to address global challenges, such as environmental sustainability and advancing technology. The core innovation lies in electrochemically designing MOF materials with tailored properties to target specific solutions. By focusing on the electrosynthesis of these materials, I explore their versatile applications in energy-related processes, such as CO₂ conversion, and in electronic devices. This approach not only advances the understanding of redox-active materials but also drives the development of scalable, sustainable technologies for pressing environmental and technological needs.

The field faces several significant challenges, including ensuring the stability of MOFs under operational conditions and achieving precise control over their properties during electrosynthesis to maintain uniformity and reproducibility. Enhancing efficiency in target applications, such as CO₂ conversion, requires improvements in selectivity, catalytic activity, and energy efficiency while balancing scalability. Integrating MOF films into functional devices presents difficulties in maintaining compatibility and material performance. Additionally, scaling up synthesis processes cost-effectively and sustainably is a major hurdle. A deeper understanding of redox mechanisms and structure-property relationships is also crucial for designing materials with targeted functionalities, alongside addressing the environmental and lifecycle impacts of these advanced materials.

I primarily enjoy spending time outdoors, walking and appreciating nature with my family. I am also a passionate fan of bouldering or tree climbing, although with a one-year-old child full of endless energy, I do not have as much time for it as I would like right now!