MS Equipment @ Campus Alameda

LCQ Fleet mass spectrometer with an ESI source (Thermo Scientific) interfaced with an HPLC-DAD (Varian)

Specifications

  • Direct infusion and HPLC interface
  • Mass range : 50 – 2000 Da
  • Unit resolution full scan (zoom scan capable)
  • Multiple fragmentation experiments, MSn (n = 10)
  • pg MS and MS/MS sensitivity

Services provided

  • Analysis and characterization of synthesized compounds including compounds with pharmacological applications
  • Analysis and characterization of low and medium molecular weight bioactive molecules in complex matrices

To use this equipment or for further information, please contact Conceição Oliveira.

QqTOF Impact II mass spectrometer with ESI and CaptiveSpray nanoBooster sources (Bruker) interfaced with a nanoLC (Dionex WPS-3000TPLRS)

Specifications

  • Direct infusion and nanoLC interface
  • Mass range: 20 – 50.000 Da
  • High resolution and high mass accuracy
  • MS/MS fragmentation experiments
  • fmol MS and MS/MS sensitivity

Services provided

  • Accurate mass measurements
  • Metabolomics
  • Protein identification by peptide mass fingerprint (PMF) and tandem MS
  • Protein post-translational modifications using middle and top-down strategies.

To use this equipment or for further information, please contact Conceição Oliveira.