Identification of the First PPAR alpha/gamma Dual Agonist Able To Bind to Canonical and Alternative Sites of PPAR gamma and To Inhibit Its Cdk5-Mediated Phosphorylation
JOURNAL OF MEDICINAL CHEMISTRY, 61, 8282-8298 9 2018
Antonio Laghezza , Luca Piemontese , Carmen Cerchia , Roberta Montanari , Davide Capelli , Marco Giudici , Maurizio Crestani , Paolo Tortorella , Franck Peiretti , Giorgio Pochetti , Antonio Lavecchia , Fulvio Loiodice

Development of a sensor for trivalent iron: AHP fixed on mesoporous silica
NEW JOURNAL OF CHEMISTRY, 42, 15237-15244 9 2018
Raffaela Biesuz , M. Amélia Santos , V. M. Nurchi , Giancarla Alberti

Synthesis, structure, solution behavior, reactivity and biological evaluation of oxidovanadium(IV/V) thiosemicarbazone complexes
DALTON TRANSACTIONS, 47, 11358-11374 9 2018
Saswati , Pedro Adão , Sudarshana Majumder , Subhashree P. Dash , Satabdi Roy , Maxim L. Kuznetsov , J.C. Pessoa , Clara S. B. Gomes , Manasi R. Hardikar , Edward R. T. Tiekink , Rupam Dinda

New salan and salen vanadium complexes: Syntheses and application in sulfoxidation catalysis
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 870, 136-144 9 2018
Minaxi S. Maru , Sonia Barroso , Pedro Adão , Luis G. Alves , Ana M. Martins

Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer s drug candidates
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 33, 1212-1224 8 2018
Luca Piemontese , Daniel Tomás , Asha Hiremathad , Vito Capriati , Emanuel Candeias , Sandra M. Cardoso , Sílvia Chaves , M. Amélia Santos

Important cytotoxic and cytostatic effects of new copper(I)-phosphane compounds with N,N, N,O and N,S bidentate ligands
DALTON TRANSACTIONS, 47, 7819-7829 6 2018
Tânia S. Morais , Yann Jousseaume , M.Fatima M.Piedade , Catarina Roma-Rodrigues , A.R. Fernandes , Fernanda M. Marques , Maria J. Villa de Brito , M. Helena Garcia

A new tripodal-3-hydroxy-4-pyridinone for iron and aluminium sequestration: synthesis, complexation and in vivo studies
NEW JOURNAL OF CHEMISTRY, 42, 8050-8061 5 2018
Rosita Cappai , Karam Chand , Joanna I. Lachowicz , Sílvia Chaves , Lurdes Gano , G. Crisponi , V. M. Nurchi , M. Peana , Maria Antonietta Zoroddu , M. Amélia Santos

Ionic liquids as promoters of fast lysozyme fibrillation
JOURNAL OF MOLECULAR LIQUIDS, 272, 456-467 12 2018
Nuno H. C. S. Silva , Ricardo J. B. Pinto , M. A. Martins , Rita Ferreira , Isabel Correia , Carmen S. R. Freire , Isabel Marrucho

Studies on the mechanism of action of antitumor bis(aminophenolate) ruthenium(III) complexes
JOURNAL OF INORGANIC BIOCHEMISTRY, 168, 27-37 3 2017
Orsolya Doemoetoer , R. F. M. de Almeida , Leonor Côrte-Real , Cristina P. Matos , Fernanda M. Marques , Antonio Matos , Carla Real , Tamas Kiss , Eve Anna Enyedy , M. Helena Garcia , Ana Isabel Tomaz

New copper(I) and heteronuclear copper(I)-ruthenium(II) complexes: Synthesis, structural characterization and cytotoxicity
JOURNAL OF INORGANIC BIOCHEMISTRY, 169, 68-78 4 2017
Joao Lopes , David Alves , Tânia S. Morais , Paulo J. Costa , M.Fatima M.Piedade , Fernanda M. Marques , Maria J. Villa de Brito , M. Helena Garcia

Synthesis of Ag(I) camphor sulphonylimine complexes and assessment of their cytotoxic properties against cisplcitin-resistant A2780cisR and A2780 cell lines
JOURNAL OF INORGANIC BIOCHEMISTRY, 166, 55-63 1 2017
Joao M. S. Cardoso , Isabel Correia , Adelino M. Galvão , Fernanda M. Marques , M Fernanda NN Carvalho

New Cu(II) complexes with pyrazolyl derived Schiff base ligands: Synthesis and biological evaluation
JOURNAL OF INORGANIC BIOCHEMISTRY, 174, 63-75 9 2017
Nádia Ribeiro , Somnath Roy , Nataliya Butenko , Isabel Cavaco , Teresa Pinheiro , Irina Alho , Fernanda M. Marques , Fernando Avecilla , J.C. Pessoa , Isabel Correia

Interaction of [(VO)-O-IV(acac)(2)] with Human Serum Transferrin and Albumin
CHEMISTRY-AN ASIAN JOURNAL, 12, 2062-2084 8 2017
Isabel Correia , Ielyzaveta Chorna , Isabel Cavaco , Somnath Roy , Maxim L. Kuznetsov , Nádia Ribeiro , Gonçalo C. Justino , Fernanda M. Marques , Teresa Santos-Silva , Marino F.A. Santos , M. Santos E. Hugo , Jose L. Capelo , James Doutch , J.C. Pessoa

Radical reactions of diamine bis(phenolate) vanadium(III) complexes. Solid state binding of O-2 to form a vanadium(V) peroxo complex
DALTON TRANSACTIONS, 46, 9692-9704 8 2017
Sonia Barroso , Ana M. Coelho , Pedro Adão , Maria Jose Calhorda , Ana M. Martins

Solution Behaviour and Catalytic Potential towards Oxidation of Dopamine by Oxidovanadium(V) Complexes of Tripodal Tetradentate Ligands
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, , 3087-3099 6 2017
Mannar R. Maurya , Bhawna Uprety , Fernando Avecilla , Pedro Adão , Maxim L. Kuznetsov , J.C. Pessoa

Evaluation of Acridine Orange Derivatives as DNA-Targeted Radiopharmaceuticals for Auger Therapy: Influence of the Radionuclide and Distance to DNA
SCIENTIFIC REPORTS, 7, 2 2017
Edgar Pereira , Leticia do Quental , E Palma , Maria Cristina Oliveira , Filipa Mendes , Paula Raposinho , Isabel Correia , Joao Lavrado , Salvatore Di Maria , Ana Belchior , Pedro Vaz , Isabel Santos , Antonio Paulo

Synthesis, biological characterization and evaluation of molecular mechanisms of novel copper complexes as anticancer agents
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1861, 218-234 2 2017
Ceyda Acilan , Buse Cevatemre , Zelal Adiguzel , Didem Karakas , Engin Ulukaya , Nádia Ribeiro , Isabel Correia , J.C. Pessoa

Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes
JOURNAL OF INORGANIC BIOCHEMISTRY, 167, 68-79 2 2017
E Palma , Filipa Mendes , Goreti Ribeiro Morais , Ines Rodrigues , Isabel Cordeiro Santos , Maria Paula C. Campello , Paula Raposinho , Isabel Correia , Sofia Gama , Dulce Belo , Vitor Alves , Antero J. Abrunhosa , Antonio Paulo

In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 17, 126-136 2017
Nuno Mendes , Francisco Tortosa , Andreia Valente , Fernanda M. Marques , Antonio Matos , Tânia S. Morais , Ana Isabel Tomaz , Fatima Gartner , M. Helena Garcia

Synthesis and Biological Evaluation of Novel 2-Aryl Benzimidazoles as Chemotherapeutic Agents
JOURNAL OF HETEROCYCLIC CHEMISTRY, 54, 255-267 1 2017
Goreti Ribeiro Morais , E Palma , Fernanda M. Marques , Lurdes Gano , Maria Cristina Oliveira , Antero J. Abrunhosa , Hugo Vicente Miranda , Tiago F. Outeiro , Isabel Santos , Antonio Paulo