| Publication Type |
Journal Article |
| Title |
Carbocation versus Carbene Controlled Chemoselectivity: DFT Study on Gold- and Silver-Catalyzed Alkylation/Cyclopropanation of Indoles with Vinyl Diazoesters |
| Authors |
Ran Fang Li Yang Lin Zhou A Kirillov Lizi Yang |
| Groups |
BioMol |
| Journal |
ORGANIC LETTERS |
| Year |
2020 |
| Month |
May |
| Volume |
22 |
| Number |
10 |
| Pages |
4043-4048 |
| Abstract |
Density functional theory calculations were performed to investigate the catalyst-controlled selective functionalization of indoles with vinyl diazoacetates. The detailed reaction mechanism was established, and different roles of carboncation or carbene intermediates in defining an experimentally observed chemo- and regioselectivity were fully rationalized. |
| DOI |
http://dx.doi.org/10.1021/acs.orglett.0c01476 |
| ISBN |
|
| Publisher |
|
| Book Title |
|
| ISSN |
1523-7060 |
| EISSN |
1523-7052 |
| Conference Name |
|
| Bibtex ID |
ISI:000535292300061 |
| Observations |
|
