Publication Type Journal Article
Title From pipemidic acid molecular salts to metal complexes and BioMOFs using mechanochemistry
Authors Martin Zabransky Paula C. Alves Catarina Bravo M. Teresa Duarte Vânia André
Groups BIOIN BIOMOL
Journal CRYSTENGCOMM
Year 2021
Month February
Volume 23
Number 5
Pages 1099-1109
Abstract Mechanochemistry has been assuming a major role in chemistry over the last years. Its potential in a wide variety of reactions is undeniable nowadays, contributing to sustainable chemistry and, at the same time, leading to lower reaction time, higher selectivity and novel reactivity. Herein we disclose new solid forms of pipemidic acid, an antibiotic against which bacteria have been developing resistance mechanisms, obtained by mechanochemistry. These forms are molecular salts with glycolic, oxalic and (R)- and (S)-camphorsulfonic acids, as well as a Cu(II) complex exhibiting a 1D hydrogen bonded network. To prove the importance of the technique, we present here also the rapid and high yielding mechanochemical synthesis of a previously reported Ag metal-organic framework with pipemidic acid.
DOI http://dx.doi.org/10.1039/d0ce01533d
ISBN
Publisher
Book Title
ISSN 1466-8033
EISSN
Conference Name
Bibtex ID ISI:000616376500004
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