Publication Type Journal Article
Title Speciation Studies of Bifunctional 3-Hydroxy-4-Pyridinone Ligands in the Presence of Zn2+ at Different Ionic Strengths and Temperatures
Authors Anna Irto Paola Cardiano Salvatore Cataldo Karam Chand Rosalia Maria Cigala Francesco Crea Concetta De Stefano Giuseppe Gattuso Nicola Muratore Alberto Pettignano Silvio Sammartano M. Amélia Santos
Groups BIOIN
Journal MOLECULES
Year 2019
Month November
Volume 24
Number 22
Pages
Abstract The acid-base properties of two bifunctional 3-hydroxy-4-pyridinone ligands and their chelating capacity towards Zn2+, an essential bio-metal cation, were investigated in NaCl aqueous solutions by potentiometric, UV-Vis spectrophotometric, and H-1 NMR spectroscopic titrations, carried out at 0.15 <= I/mol (-1) <= 1.00 and 288.15 <= T/K <= 310.15. A study at I = 0.15 mol L-1 and T = 298.15 K was also performed for other three Zn2+/Lz- systems, with ligands belonging to the same family of compounds. The processing of experimental data allowed the determination of protonation and stability constants, which showed accordance with the data obtained from the different analytical techniques used, and with those reported in the literature for the same class of compounds. ESI-MS spectrometric measurements provided support for the formation of the different Zn2+/ligand species, while computational molecular simulations allowed information to be gained on the metal-ligand coordination. The dependence on ionic strength and the temperature of equilibrium constants were investigated by means of the extended Debye-Huckel model, the classical specific ion interaction theory, and the van t Hoff equations, respectively.
DOI http://dx.doi.org/10.3390/molecules24224084
ISBN
Publisher
Book Title
ISSN
EISSN 1420-3049
Conference Name
Bibtex ID ISI:000501529700073
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