| Publication Type |
Journal Article |
| Title |
Catalyst-dependent selectivity in sulfonium ylide cycloisomerization reactions |
| Authors |
Rik Oost James D. Neuhaus Antonio Misale Ricardo Meyrelles Luis F. Veiros Nuno Maulide |
| Groups |
IOARC |
| Journal |
CHEMICAL SCIENCE |
| Year |
2018 |
| Month |
September |
| Volume |
9 |
| Number |
35 |
| Pages |
7091-7095 |
| Abstract |
Divergent catalysis is an emerging field whereby access to structurally diverse compounds from a common precursor is achieved through controlled reaction pathways. Herein we present an unusual example of -acid catalyst dependent selectivity in the cycloisomerization of alkene-tethered sulfonium ylides. Computational mechanistic studies revealed how the ability of palladium to cycle through oxidation states largely controls the selectivity. |
| DOI |
http://dx.doi.org/10.1039/c8sc02815j |
| ISBN |
|
| Publisher |
|
| Book Title |
|
| ISSN |
2041-6520 |
| EISSN |
2041-6539 |
| Conference Name |
|
| Bibtex ID |
ISI:000445777400007 |
| Observations |
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