| Publication Type |
Journal Article |
| Title |
Synthesis and Biological Evaluation of Novel Chalcone-Porphyrin Conjugates |
| Authors |
Vanda Vaz Serra Fatima Camoes Sandra I. Vieira Maria A. F. Faustino João P. C. Tomé Diana C. G. A. Pinto M. Graca P. M. S. Neves Augusto C. Tome Artur M. S. Silva Edgar F. da Cruz e Silva Jose A. S. Cavaleiro |
| Groups |
|
| Journal |
ACTA CHIMICA SLOVENICA |
| Year |
2009 |
| Month |
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|
| Volume |
56 |
| Number |
3 |
| Pages |
603-611 |
| Abstract |
Studies on the synthesis, structural characterization and biological evaluation of novel chalcone-porphyrin derivatives are described. The photodynamic effect, intracellular localization and cellular uptake of the new conjugates were evaluated in vitro in COS-7 cells. All derivatives exhibited high stability and yielded good fluorescence under light irradiation. None of the chalcone-porphyrins proved to be cytotoxic and/or phototoxic for COS-7 cells. |
| DOI |
http://dx.doi.org/ |
| ISBN |
|
| Publisher |
|
| Book Title |
|
| ISSN |
1318-0207 |
| EISSN |
|
| Conference Name |
|
| Bibtex ID |
ISI:000270787600011 |
| Observations |
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