| Publication Type |
Journal Article |
| Title |
Impact of Inosine Triphosphatase Gene Variants on the Risk of Anemia in HIV/Hepatitis C Virus-Coinfected Patients Treated for Chronic Hepatitis C |
| Authors |
Norma I. Rallon Judit Morello Pablo Labarga Jose M. Benito Sonia Rodriguez-Novoa Eugenia Vispo Pablo Barreiro M. Angeles Castro Koldo Aguirrebengoa Juan A. Pineda P. Miralles M. Jesus Tellez Joaquin Portu Celia Miralles Antonio Ocampo Vincent Soriano Peginterferon Ribavirin Coinfect T |
| Groups |
|
| Journal |
CLINICAL INFECTIOUS DISEASES |
| Year |
2011 |
| Month |
December |
| Volume |
53 |
| Number |
12 |
| Pages |
1291-1295 |
| Abstract |
The role of rs1127354/rs7270101 alleles at the inosine triphosphatase (ITPA) gene on ribavirin-induced anemia was assessed in 74 patients with hepatitis C virus and human immunodeficiency virus coinfection. Anemia developed in 80\% of patients with normal ITPA activity compared with 33\% of those with reduced ITPA activity. In contrast, ITPA variants did not influence sustained virological response. |
| DOI |
http://dx.doi.org/10.1093/cid/cir665 |
| ISBN |
|
| Publisher |
|
| Book Title |
|
| ISSN |
1058-4838 |
| EISSN |
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| Conference Name |
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| Bibtex ID |
ISI:000297279700021 |
| Observations |
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