A novel screening method for transition metal-based anticancer compounds using zebrafish embryo-larval assay and inductively coupled plasma-mass spectrometry analysis
JOURNAL OF APPLIED TOXICOLOGY, 39, 1173-1180 8 2019
Brittany F. Karas , Leonor Côrte-Real , Cathleen L. Doherty , Andreia Valente , Keith R. Cooper , Brian T. Buckley

Ruthenium-Cyclopentadienyl Bipyridine-Biotin Based Compounds: Synthesis and Biological Effect
INORGANIC CHEMISTRY, 58, 9135-9149 7 2019
Leonor Côrte-Real , Brittany Karas , Ana Rita Brás , Adhan Pilon , Fernando Avecilla , Fernanda Marques , Ana Preto , Brian T. Buckley , Keith R. Cooper , Cathleen Doherty , M. Helena Garcia , Andreia Valente

Polymer ruthenium-cyclopentadienyl conjugates - New emerging anti-cancer drugs
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 168, 373-384 4 2019
Tiago Moreira , Rita Francisco , Elisabeta Comsa , Sophie Duban-Deweer , Valerie Labas , Ana-Paula Teixeira-Gomes , Lucie Combes-Soia , Fernanda M. Marques , Antonio Matos , Audrey Favrelle , Cyril Rousseau , Philippe Zinck , Pierre Falson , M. Helena Garcia , Ana Preto , Andreia Valente

New Cyclams and Their Copper(II) and Iron(III) Complexes: Synthesis and Potential Application as Anticancer Agents
CHEMMEDCHEM, 14, 770-778 4 2019
Adhan Pilon , Julia Lorenzo , Sergi Rodriguez-Calado , Pedro Adão , Ana M. Martins , Andreia Valente , Luis G. Alves

Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 163, 853-863 2 2019
Leonor Côrte-Real , Brittany Karas , Patricia Girio , Alexis Moreno , Fernando Avecilla , Fernanda M. Marques , Brian T. Buckley , Keith R. Cooper , Cathleen Doherty , Pierre Falson , M. Helena Garcia , Andreia Valente

Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 19, 1262-1275 2019
Lurdes Gano , Teresa Pinheiro , Antonio P. Matos , Francisco Tortosa , Tiago F. Jorge , Maria S. Goncalves , Marta Martins , Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Maria H. Garcia , Fernanda M. Marques

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells
European Journal of Medicinal Chemistry , 143, 503-514 2018
Ricardo G. Teixeira , Ana Rita Brás , Leonor Côrte-Real , Rajendhraprasad Tatikonda , Anabela Sanches , M Paula Robalo , Fernado Avecilla , Tiago Moreira , M. Helena Garcia , Matti Haukka , Ana Preto , Andreia Valente

Methyl-cyclopentadienyl Ruthenium Compounds with 2,2?-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential
Inorganic Chemistry, , 4 2018
Leonor Côrte-Real , Ricardo G. Teixeira , Patricia Girio , Elisabeta Comsa , Alexis Moreno , Rachad Nasr , Hélène Baubichon-Cortay , Fernando Avecilla , Fernanda M. Marques , M Paula Robalo , Paulo Mendes , Joao P. Prates Ramalho , M. Helena Garcia , Pierre Falson , Andreia Valente

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 143, 503-514 1 2018
Ricardo G. Teixeira , Ana Rita Brás , Leonor Côrte-Real , Rajendhraprasad Tatikonda , Anabela Sanches , M Paula Robalo , Fernando Avecilla , Tiago Moreira , M. Helena Garcia , Matti Haukka , Ana Preto , Andreia Valente

In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 17, 126-136 2017
Nuno Mendes , Francisco Tortosa , Andreia Valente , Fernanda M. Marques , Antonio Matos , Tânia S. Morais , Ana Isabel Tomaz , Fatima Gartner , M. Helena Garcia

New iron cyclopentadienyl complexes bearing different phosphane co-ligands: Structural factors vs. cytotoxicity
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 852, 34-42 12 2017
Adhan Pilon , Patricia Girio , Guilherme Nogueira , Fernando Avecilla , Harry Adams , Julia Lorenzo , M. Helena Garcia , Andreia Valente

Silica-Grafted Lanthanum Benzyl Species: Synthesis, Characterization, and Catalytic Applications
ORGANOMETALLICS, 36, 3912-3920 10 2017
Tom Vancompernolle , Andreia Valente , Thomas Chenal , Philippe Zinck , Iker Del Rosal , Laurent Maron , Mostafa Taoufik , Sjoerd Harder , Regis M. Gauvin

eta(6)-(2-phenoxyethanol) ruthenium(II)-complexes of 2,2 -bipyridine and its derivatives: Solution speciation and kinetic behaviour
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 820, 20-29 10 2016
Guilherme Nogueira , Orsolya Domotor , Adhan Pilon , M Paula Robalo , Fernando Avecilla , M. Helena Garcia , Eva A. Enyedy , Andreia Valente

Adenine as an organocatalyst for the ring-opening polymerization of lactide: scope, mechanism and access to adenine-functionalized polylactide
REACTION CHEMISTRY \& ENGINEERING, 1, 508-520 2016
Guilherme Nogueira , Audrey Favrelle , Marc Bria , Joao P. Prates Ramalho , Paulo Mendes , Andreia Valente , Philippe Zinck

Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds
FUTURE MEDICINAL CHEMISTRY, 8, 527-544 2016
Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Fernanda M. Marques , M. Helena Garcia

The key role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: Ranging from non-cytotoxic to highly cytotoxic compounds
JOURNAL OF INORGANIC BIOCHEMISTRY, 150, 148-159 9 2015
Leonor Côrte-Real , M Paula Robalo , Fernanda M. Marques , Guilherme Nogueira , Fernando Avecilla , Tiago J. L. Silva , Filipa C. Santos , Ana Isabel Tomaz , M. Helena Garcia , Andreia Valente

New iron(II) cyclopentadienyl derivative complexes: Synthesis and antitumor activity against human leukemia cancer cells
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 756, 52-60 4 2014
Andreia Valente , Ana Margarida Santos , Leonor Côrte-Real , M Paula Robalo , Virtudes Moreno , Merce Font-Bardia , Teresa Calvet , Julia Lorenzo , M. Helena Garcia

Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 19, 853-867 8 2014
Leonor Côrte-Real , Filipa Mendes , Joana Coimbra , Tânia S. Morais , Ana Isabel Tomaz , Andreia Valente , M. Helena Garcia , Isabel Santos , Manuel Bicho , Fernanda M. Marques

Isoprene- Styrene Chain Shuttling Copolymerization Mediated by a Lanthanide Half- Sandwich Complex and a Lanthanidocene: Straightforward Access to a New Type of Thermoplastic Elastomers
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 53, 4638-4641 4 2014
Andreia Valente , Gregory Stoclet , Fanny Bonnet , Andre Mortreux , Marc Visseaux , Philippe Zinck

Synthesis of new Fe(II) and Ru(II) eta(5)-monocyclopentadienyl compounds showing significant second order NLO properties
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 736, 42-49 7 2013
Andreia Valente , Sophie Royer , Milan Narendra , Tiago J. L. Silva , Paulo Mendes , M Paula Robalo , Manuel Abreu , Juergen Heck , M. Helena Garcia