A New Family of Iron(II)-Cyclopentadienyl Compounds Shows Strong Activity against Colorectal and Triple Negative Breast Cancer Cells
MOLECULES, 25, 4 2020
Adhan Pilon , Ana Rita Brás , Leonor Côrte-Real , Fernando Avecilla , Paulo J. Costa , Ana Preto , M. Helena Garcia , Andreia Valente

Synthesis, Characterization and Anticancer Studies of Rh(I), Rh(III), Pd(II) and Pt(II) Complexes Bearing A Dithiooxamide Ligand
CHEMISTRYSELECT, 5, 810-817 1 2020
Banafshe Askari , Hadi Amiri Rudbari , Andreia Valente , Giuseppe Bruno , Nicola Micale , Naveen Shivalingegowda , Lokanath Neratur Krishnappagowda

A novel screening method for transition metal-based anticancer compounds using zebrafish embryo-larval assay and inductively coupled plasma-mass spectrometry analysis
JOURNAL OF APPLIED TOXICOLOGY, 39, 1173-1180 8 2019
Brittany F. Karas , Leonor Côrte-Real , Cathleen L. Doherty , Andreia Valente , Keith R. Cooper , Brian T. Buckley

New Cyclams and Their Copper(II) and Iron(III) Complexes: Synthesis and Potential Application as Anticancer Agents
CHEMMEDCHEM, 14, 770-778 4 2019
Adhan Pilon , Julia Lorenzo , Sergi Rodriguez-Calado , Pedro Adão , Ana M. Martins , Andreia Valente , Luis G. Alves

Ruthenium-Cyclopentadienyl Bipyridine-Biotin Based Compounds: Synthesis and Biological Effect
INORGANIC CHEMISTRY, 58, 9135-9149 7 2019
Leonor Côrte-Real , Brittany Karas , Ana Rita Brás , Adhan Pilon , Fernando Avecilla , Fernanda Marques , Ana Preto , Brian T. Buckley , Keith R. Cooper , Cathleen Doherty , M. Helena Garcia , Andreia Valente

Unprecedented inhibition of P-gp activity by a novel ruthenium-cyclopentadienyl compound bearing a bipyridine-biotin ligand
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 163, 853-863 2 2019
Leonor Côrte-Real , Brittany Karas , Patricia Girio , Alexis Moreno , Fernando Avecilla , Fernanda M. Marques , Brian T. Buckley , Keith R. Cooper , Cathleen Doherty , Pierre Falson , M. Helena Garcia , Andreia Valente

Polymer ruthenium-cyclopentadienyl conjugates - New emerging anti-cancer drugs
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 168, 373-384 4 2019
Tiago Moreira , Rita Francisco , Elisabeta Comsa , Sophie Duban-Deweer , Valerie Labas , Ana-Paula Teixeira-Gomes , Lucie Combes-Soia , Fernanda M. Marques , Antonio Matos , Audrey Favrelle , Cyril Rousseau , Philippe Zinck , Pierre Falson , M. Helena Garcia , Ana Preto , Andreia Valente

Antitumour and Toxicity Evaluation of a Ru(II)-Cyclopentadienyl Complex in a Prostate Cancer Model by Imaging Tools
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 19, 1262-1275 2019
Lurdes Gano , Teresa Pinheiro , Antonio P. Matos , Francisco Tortosa , Tiago F. Jorge , Maria S. Goncalves , Marta Martins , Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Maria H. Garcia , Fernanda M. Marques

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells
European Journal of Medicinal Chemistry , 143, 503-514 2018
Ricardo G. Teixeira , Ana Rita Brás , Leonor Côrte-Real , Rajendhraprasad Tatikonda , Anabela Sanches , M Paula Robalo , Fernado Avecilla , Tiago Moreira , M. Helena Garcia , Matti Haukka , Ana Preto , Andreia Valente

Methyl-cyclopentadienyl Ruthenium Compounds with 2,2?-Bipyridine Derivatives Display Strong Anticancer Activity and Multidrug Resistance Potential
Inorganic Chemistry, , 4 2018
Leonor Côrte-Real , Ricardo G. Teixeira , Patricia Girio , Elisabeta Comsa , Alexis Moreno , Rachad Nasr , Hélène Baubichon-Cortay , Fernando Avecilla , Fernanda M. Marques , M Paula Robalo , Paulo Mendes , Joao P. Prates Ramalho , M. Helena Garcia , Pierre Falson , Andreia Valente

Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 143, 503-514 1 2018
Ricardo G. Teixeira , Ana Rita Brás , Leonor Côrte-Real , Rajendhraprasad Tatikonda , Anabela Sanches , M Paula Robalo , Fernando Avecilla , Tiago Moreira , M. Helena Garcia , Matti Haukka , Ana Preto , Andreia Valente

In Vivo Performance of a Ruthenium-cyclopentadienyl Compound in an Orthotopic Triple Negative Breast Cancer Model
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 17, 126-136 2017
Nuno Mendes , Francisco Tortosa , Andreia Valente , Fernanda M. Marques , Antonio Matos , Tânia S. Morais , Ana Isabel Tomaz , Fatima Gartner , M. Helena Garcia

New iron cyclopentadienyl complexes bearing different phosphane co-ligands: Structural factors vs. cytotoxicity
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 852, 34-42 12 2017
Adhan Pilon , Patricia Girio , Guilherme Nogueira , Fernando Avecilla , Harry Adams , Julia Lorenzo , M. Helena Garcia , Andreia Valente

Silica-Grafted Lanthanum Benzyl Species: Synthesis, Characterization, and Catalytic Applications
ORGANOMETALLICS, 36, 3912-3920 10 2017
Tom Vancompernolle , Andreia Valente , Thomas Chenal , Philippe Zinck , Iker Del Rosal , Laurent Maron , Mostafa Taoufik , Sjoerd Harder , Regis M. Gauvin

Ruthenium new drug: paving the way for cancer therapy
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 22, S122 7 2017
Maria Helena Garcia , Andreia Valente , Tânia S. Morais , Ana Isabel Tomaz

Cancer targeted therapy: the next generation of metallodrugs
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 22, S115 7 2017
Andreia Valente , Tiago Moreira , Ana R. Bras , Ana Preto , M. Helena Garcia

eta(6)-(2-phenoxyethanol) ruthenium(II)-complexes of 2,2 -bipyridine and its derivatives: Solution speciation and kinetic behaviour
JOURNAL OF ORGANOMETALLIC CHEMISTRY, 820, 20-29 10 2016
Guilherme Nogueira , Orsolya Domotor , Adhan Pilon , M Paula Robalo , Fernando Avecilla , M. Helena Garcia , Eva A. Enyedy , Andreia Valente

Adenine as an organocatalyst for the ring-opening polymerization of lactide: scope, mechanism and access to adenine-functionalized polylactide
REACTION CHEMISTRY \& ENGINEERING, 1, 508-520 2016
Guilherme Nogueira , Audrey Favrelle , Marc Bria , Joao P. Prates Ramalho , Paulo Mendes , Andreia Valente , Philippe Zinck

Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds
FUTURE MEDICINAL CHEMISTRY, 8, 527-544 2016
Tânia S. Morais , Andreia Valente , Ana Isabel Tomaz , Fernanda M. Marques , M. Helena Garcia

The key role of coligands in novel ruthenium(II)-cyclopentadienyl bipyridine derivatives: Ranging from non-cytotoxic to highly cytotoxic compounds
JOURNAL OF INORGANIC BIOCHEMISTRY, 150, 148-159 9 2015
Leonor Côrte-Real , M Paula Robalo , Fernanda M. Marques , Guilherme Nogueira , Fernando Avecilla , Tiago J. L. Silva , Filipa C. Santos , Ana Isabel Tomaz , M. Helena Garcia , Andreia Valente