Sex differences in hepatic and intestinal contributions to nevirapine biotransformation in rats
CHEMICO-BIOLOGICAL INTERACTIONS, 233, 115-121 5 2015
Pedro F. Pinheiro , A. T. Marinho , Alexandra Maria Moita Antunes , M. Matilde Marques , S. A. Pereira , Joana P. Miranda

Quinoid derivatives of the nevirapine metabolites 2-hydroxy- and 3-hydroxy-nevirapine: activation pathway to amino acid adducts
TOXICOLOGY RESEARCH, 4, 1565-1577 2015
Shrika G. Harjivan , Pedro F. Pinheiro , Inês Sofia Lança Martins , Ana L. Godinho , Riccardo Wanke , P P Santos , Sofia A. Pereira , Frederick A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

ANTI-HISTONE ANTIBODIES IN HIV-INFECTED PATIENTS ON NEVIRAPINE-CONTAINING ANTIRETROVIRAL THERAPY
CLINICAL THERAPEUTICS, 37, E142 8 2015
S. A. Pereira , Alexandra Maria Moita Antunes , C. G. Dias , A. T. Marinho , S. G. Harjivan , M. Fonseca , S. Maia , T. Branco , U. Caixas , M. Matilde Marques , E. C. Monteiro

First in vitro evidence for a catechol metabolite from the anti-HIV drug efavirenz - A plausible role in toxicity
TOXICOLOGY LETTERS, 238, S360 10 2015
S. G. Harjivan , R. Wanke , K. Woodling , G. Gamboa da Costa , F. A. Beland , Alexandra Maria Moita Antunes , M. Matilde Marques

Enzymatic bioactivation of the phenolic nevirapine metabolites 2-hydroxy- and 3-hydroxy-nevirapine to quinoid intermediates: Covalent adduct formation with nitrogen-based amino acids
TOXICOLOGY LETTERS, 238, S359-S360 10 2015
S. G. Harjivan , Pedro F. Pinheiro , Inês Sofia Lança Martins , D. A. Novais , R. Wanke , P P Santos , S. A. Pereira , F. A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

Thiol status in HIV-infected patients: The effect of nevirapine metabolism
TOXICOLOGY LETTERS, 229, S95 9 2014
Clara G. Dias , Aline T. Marinho , Umbelina Caixas , Ines Faustino , Alexandra Maria Moita Antunes , M. Matilde Marques , Emilia C. Monteiro , Sofia A. Pereira

An animal model to explore efavirenz toxicokinetics and its relation to neurological phenotype
TOXICOLOGY LETTERS, 229, S244 9 2014
Nadia M. Grilo , Vania L. Batalha , Luisa V. Lopes , M. Matilde Marques , Emilia C. Monteiro , Alexandra Maria Moita Antunes , Sofia A. Pereira

PON-1 activity as a protective player in nevirapine hepatotoxicity: Data comparison in 2D and 3D cell cultures
TOXICOLOGY LETTERS, 229, S134-S135 9 2014
Aline T. Marinho , Clara G. Dias , Pedro F. Pinheiro , Alexandra Maria Moita Antunes , M. Matilde Marques , Emilia C. Monteiro , Joana P. Miranda , Sofia A. Pereira

Sex differences in hepatic and intestinal contributions for nevirapine biotransformation
TOXICOLOGY LETTERS, 229, S240-S241 9 2014
Pedro F. Pinheiro , Aline T. Marinho , Alexandra Maria Moita Antunes , M. Matilde Marques , Matilde F. Castro , Sofia A. Pereira , Joana P. Miranda

Covalent histone modification by nevirapine: Potential association with non-AIDS defining cancers
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 248, 8 2014
Shrika G. Harjivan , Catarina Sofia Romão Charneira , Sofia A. Pereira , Guadalupe Espadas , Eduard Sabido , Frederick A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

The phenolic metabolites of the anti-HIV drug efavirenz: Evidence for distinct reactivities upon oxidation with Fremy s salt
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 74, 7-11 3 2014
Shrika G. Harjivan , Riccardo Wanke , João Ferreira da Silva , M. Matilde Marques , Alexandra Maria Moita Antunes

Bioactivation to an aldehyde metabolite-Possible role in the onset of toxicity induced by the anti-HIV drug abacavir
TOXICOLOGY LETTERS, 224, 416-423 1 2014
Nadia M. Grilo , Catarina Sofia Romão Charneira , Sofia A. Pereira , Emilia C. Monteiro , M. Matilde Marques , Alexandra Maria Moita Antunes

Differences in nevirapine biotransformation as a factor for its sex-dependent dimorphic profile of adverse drug reactions
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 69, 476-482 2 2014
Aline T. Marinho , Patrcia M. Rodrigues , Umbelina Caixas , Alexandra Maria Moita Antunes , Teresa Branco , Shrika G. Harjivan , M. Matilde Marques , Emlia C. Monteiro , Sofia A. Pereira

Chlorinated Polycyclic Aromatic Hydrocarbons Associated with Drinking Water Disinfection: Synthesis, Formation under Aqueous Chlorination Conditions and Genotoxic Effects
POLYCYCLIC AROMATIC COMPOUNDS, 34, 356-371 2014
Miguel Pinto , Marlene Rebola , Henriqueta Louro , Alexandra Maria Moita Antunes , Silvia S. Jose , Maria Rocha , Maria Joao Silva , Ana Sofia Cardoso

Development and validation of an HPLC-UV method for quantifying nevirapine and its main phase I metabolites in human blood
ANALYTICAL METHODS, 6, 1575-1580 2014
Aline T. Marinho , Ana L. A. Godinho , David A. Novais , Alexandra Maria Moita Antunes , M. Matilde Marques , Teresa Ramos , Clara G. Dias , Emilia C. Monteiro , Sofia A. Pereira

Quantification of the arylesterase activity of paraoxonase-1 in human blood
ANALYTICAL METHODS, 6, 289-294 2014
Clara G. Dias , Joana R. Batuca , Aline T. Marinho , Umbelina Caixas , Emilia C. Monteiro , Alexandra Maria Moita Antunes , Sofia A. Pereira

Electronic Communication in Linear Oligo(azobenzene) Radical Anions
JOURNAL OF PHYSICAL CHEMISTRY A, 117, 14056-14064 12 2013
Alvaro Moneo , Gonçalo C. Justino , M Fernanda NN Carvalho , M. Conceição Oliveira , Alexandra Maria Moita Antunes , David Bleger , Stefan Hecht , J. P. Telo

Estrogen-induced systemic lupus erythematosus: Understanding the role of protein adducts in autoimmunity
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 246, 9 2013
Catarina Sofia Romão Charneira , Sofia A. Pereira , Alexandra Maria Moita Antunes , M. Matilde Marques

3D hepatocyte cultures: A useful tool in the study of Nevirapine bioactivation and toxicity
TOXICOLOGY LETTERS, 221, S174 8 2013
Joana P. Miranda , Pedro F. Pinheiro , A. T. Marinho , S. G. Harjivan , Matilde Castro , S. A. Pereira , Alexandra Maria Moita Antunes , M. Matilde Marques

Synthesis and evaluation of diaryl sulfides and diaryl selenide compounds for antitubulin and cytotoxic activity
BIOORGANIC \& MEDICINAL CHEMISTRY LETTERS, 23, 4669-4673 8 2013
Edson dos A. dos Santos , Ernest Hamel , Ruoli Bai , James C. Burnett , Camila Santos Suniga Tozatti , Danielle Bogo , Renata T. Perdomo , Alexandra Maria Moita Antunes , M. Matilde Marques , Maria de F. C. Matos , Denis P. de Lima